Our last paper has been published:
Casal J., Storer F., and Lawrence, P.A. Planar cell polarity: intracellular asymmetry and supracellular gradients of Frizzled. Open Biology 13: 230105 (2023).
News
Our last paper (so far?) on Planar Cell Polarity:
Chorro A., Verma B., Homfeldt M., Ibáñez B., Lawrence P.A., and Casal J. Planar cell polarity: intracellular asymmetry and supracellular gradients of Dachsous Open Biology 12: 20195 (2022)
The slope of a supracellular molecular gradient has long been thought to orient and coordinate planar cell polarity (PCP). Here we demonstrate and measure that gradient. Dachsous (Ds) is a conserved and elemental molecule of PCP; Ds forms intercellular bridges with another cadherin molecule,
Chorro A., Verma B., Homfeldt M., Ibáñez B., Lawrence P.A., and Casal J. Planar cell polarity: intracellular asymmetry and supracellular gradients of Dachsous Open Biology 12: 20195 (2022)
The slope of a supracellular molecular gradient has long been thought to orient and coordinate planar cell polarity (PCP). Here we demonstrate and measure that gradient. Dachsous (Ds) is a conserved and elemental molecule of PCP; Ds forms intercellular bridges with another cadherin molecule,
Due to the lack of funds our lab will be closing down at the end of 2022. Thanks for your support.
We are applying for grants to support our research during the 2021-2023 period. Any prospective student willing to do a PhD with us should contact us in November or December 2020.
A preprint of our last article is deposited in bioRxiv:
Pietra S., Ng K., Lawrence P.A. and Casal J. How do Dachsous and Fat polarise cells in the larval abdomen of Drosophila? bioRxiv (2020).
A preprint of our rebuttal of Abbasi and Marcus in Scientific Reports
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